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L-cystine is recommended in the treatment of various forms of hair disorders
- L-cystine is the principal protein component of keratin, the main hair protein which contains 17,5% of L-cystine
- Clinical nutrition trials demonstrate interest of daily supplementation with 500 mg L-cystine (preferably associated with B-vitamins, zinc, and retinol).
- Significant decrease in L-cystine (2–14%) has been reported in human hair treated with permanent-waving products.
- Hair relaxers use is associated with reduced L-cystine content (56 to 88%), consistent with fragile damaged hair.
L-cystine is regarded as a nail revitalizing agent
- Nails are composed of a high sulfur type of keratin, containing up to 18% L-cystine.
- The nail grows approximately 2 to 3 mm per month (i.e. 0,1 mm daily) with complete replacement achieved in 6 to 9 months.
L-cystine is a precursor of GSH, one of the most important body antioxidant.
- Increasing the supply of L-cystine prevents GSH deficiency under various nutritional and pathological conditions (including protein malnutrition, adult respiratory distress syndrome,HIV, and AIDS)
- GSH levels in normal lenses decrease gradually with increasing age.
- GSH is depleted in cataract: the number of protein thiol groups is less than 10% of that found in normal lens.
- Critically ill patients receiving enteral or parenteral nutrition, enriched with L-cystine, exhibit improved GSH synthesis.